Use of the BacT/Alert System for Rapid Detection of Microbial Contamination in a Pilot Study Using Pancreatic Islet Cell Products | Zendy

Laura Murray | Zendy; Neil McGowan | Zendy; John O. Fleming | Zendy; Laura Bailey | Zendy

Open Access

Use of the BacT/Alert System for Rapid Detection of Microbial Contamination in a Pilot Study Using Pancreatic Islet Cell Products

Author(s) -

Laura Murray,

Neil McGowan,

John O. Fleming,

Laura Bailey

Publication year - 2014

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00447-14

Subject(s) - islet , sterility , pancreas , contamination , biology , medicine , microbiology and biotechnology , insulin , ecology , genetics

At the Islet Isolation Laboratory of the Scottish National Blood Transfusion Service, manual sterility testing data show that contamination rates are 57.7% for pancreas transport fluid, 4.3% for postpurification islet samples, and 0% for pretransplant islet samples. This pilot study presents the BacT/Alert System as an alternative to manual testing to provide more rapid and sensitive sterility results for islet cell products.

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