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We describe a 22-year-old soldier with 19% total body surface area burns, polytrauma, and sequence- and culture-confirmedPythium aphanidermatum wound infection. Antemortem histopathology suggested disseminatedPythium infection, including brain involvement; however, postmortem PCR revealedCunninghamella elegans ,Lichtheimia corymbifera , andSaksenaea vasiformis coinfection. The utility of molecular diagnostics in invasive fungal infections is discussed.

Combat-Related Pythium aphanidermatum Invasive Wound Infection: Case Report and Discussion of Utility of Molecular Diagnostics