Open AccessToxin Profiles and Resistances to Macrolides and Newer Fluoroquinolones as Epidemicity Determinants of Clinical Isolates of Clostridium difficile from Warsaw, Poland
Author(s) -
Hanna Pituch,
Willem van Leeuwen,
Kees Maquelin,
Dorota Wultańska,
Piotr Obuch-Woszczatyński,
Grażyurzyńska,
Haru Kato,
Martin Reijans,
F Meisel-Mikołajczyk,
M. Łuczak,
Alex van Belkum
Publication year - 2007
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00306-07
Subject(s) - clostridium difficile , microbiology and biotechnology , clostridium infections , clostridiaceae , toxin , clinical microbiology , clostridium difficile toxin a , medicine , biology , antibiotics
Amplified fragment length polymorphism genotypes, antibiotic resistance profiles, and toxin profiles ofClostridium difficile strains from Warsaw were determined. The isolates segregate in six major genotypes, coinciding with toxin profiles. Most of the toxin A-negative toxin B-positive toxin CDT-negative strains possessermB , and several strains were resistant to fluoroquinolones. Resistograms and toxin types ofC. difficile strains are epidemicity determinants.