Evaluation of Simplexa Flu A/B & RSV for Direct Detection of Influenza Viruses (A and B) and Respiratory Syncytial Virus in Patient Clinical Samples | Zendy

Musa Hindiyeh | Zendy; Liat Kolet | Zendy; Tal Meningher | Zendy; Merav Weil | Zendy; Ella Mendelson | Zendy; Michal Mandelboim | Zendy

Open Access

Evaluation of Simplexa Flu A/B & RSV for Direct Detection of Influenza Viruses (A and B) and Respiratory Syncytial Virus in Patient Clinical Samples

Author(s) -

Musa Hindiyeh,

Liat Kolet,

Tal Meningher,

Merav Weil,

Ella Mendelson,

Michal Mandelboim

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00286-13

Subject(s) - virology , respiratory system , virus , paramyxoviridae , orthomyxoviridae , influenza a virus , medicine , mononegavirales , covid-19 , influenzavirus b , positive predicative value , predictive value , microbiology and biotechnology , biology , viral disease , disease , infectious disease (medical specialty)

We evaluated the performance of the Simplexa Flu A/B & RSV kit on 170 prospective respiratory samples using a modified protocol, supplied by the manufacturer, that eliminates the RNA extraction step. Overall, compared against our laboratory-developed assay, the assay's sensitivity, specificity, and positive and negative predictive values were 95.1%, 99.6%, 98.7%, and 98.6%, respectively.

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