Open AccessPerformance of the Roche LightCycler Real-Time PCR Assay for Diagnosing Extrapulmonary Tuberculosis
Author(s) -
Natasha Gous,
Lesley Scott,
Emily Wong,
Tanvier Omar,
François Venter,
Wendy Stevens
Publication year - 2012
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00252-12
Subject(s) - mycobacterium tuberculosis , tuberculosis , pathology , roche diagnostics , mycobacterium kansasii , mycobacterium , biopsy , medicine , bone marrow , polymerase chain reaction , biology , gene , biochemistry
The Roche LightCycler mycobacterium detection molecular assay for Mycobacterium tuberculosis, M. avium, and M. kansasii, was applied to tissue specimens. It performed well on lymph node and cerebrospinal fluid specimens and less well on lung, liver, and bone marrow core biopsy specimens, but used in conjunction with a clinical suspicion of tuberculosis, it could augment patient management.
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