Open AccessThree Clustered Cases of Candidemia Caused by Candida quercitrusa and Mycological Characteristics of This Novel Species
Author(s) -
Meng Xiao,
He Wang,
Juan Lü,
Sharon C.-A. Chen,
Fanrong Kong,
Xiaojun Ma,
Yingchun Xu
Publication year - 2014
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00246-14
Subject(s) - microbiology and biotechnology , fungemia , fungi imperfecti , mycosis , biology , echinocandins , medicine , antifungal , amphotericin b , caspofungin , immunology
We investigated three nosocomialCandida quercitrusa candidemia cases occurring within 2 months in a Chinese hospital. Isolates were identifiable only by DNA sequencing of the rRNA genes. Genetic (via random amplified polymorphic DNA [RAPD]) and protein mass spectral (via matrix-assisted laser desorption ionization–time of flight mass spectrometry [MALDI-TOF MS]) analyses yielded identical profiles suggesting an outbreak. The fluconazole MICs of all the strains were 16 to 32 μg/ml.
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