Open AccessSimple Assay for Detection of the Central Asia Outbreak Clade of the Mycobacterium tuberculosis Beijing Genotype
Author(s) -
Egor Shitikov,
Anna Vyazovaya,
Maja V. Malakhova,
Andrei Guliaev,
Julia Bespyatykh,
Е. С. Прошина,
О. А. Пасечник,
Igor Mokrousov
Publication year - 2019
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00215-19
Subject(s) - mycobacterium tuberculosis , clade , outbreak , tuberculosis , virology , genotype , biology , molecular epidemiology , beijing , european union , genetics , medicine , phylogenetic tree , gene , geography , china , archaeology , pathology , business , economic policy
The Central Asia outbreak (CAO) clade is a branch of theMycobacterium tuberculosis Beijing genotype that is associated with multidrug resistance, increased transmissibility, and epidemic spread in parts of the former Soviet Union. Furthermore, migration flows bring these strains far beyond their areas of origin.
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