Open AccessUncommon Neosartorya udagawae Fungus as a Causative Agent of Severe Corneal Infection
Author(s) -
Brunella Posteraro,
Romano Mattei,
Fausto Trivella,
Andrea Maffei,
Antonio La Torre,
Elena De Carolis,
Brunella Posteraro,
Giovanni Fadda
Publication year - 2011
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00134-11
Subject(s) - itraconazole , fluconazole , aspergillus fumigatus , fungus , keratitis , endophthalmitis , microbiology and biotechnology , mycosis , fungal keratitis , biology , antifungal , fungi imperfecti , amphotericin b , medicine , dermatology , surgery , immunology , botany
We report the first documented case of a posttraumatic fungal keratitis caused by Neosartorya udagawae. The patient was empirically treated with fluconazole until a corneal scraping grew an Aspergillus fumigatus-like fungus, and itraconazole therapy was then established. A sequence-based approach assigned the isolate to the species. Five months after completion of antifungal therapy, endophthalmitis occurred and orbital exenteration was necessary.