Open AccessEvidence for Reactivation of Human Herpesvirus 6 in Generalized Lymphadenopathy in a Patient with Drug-Induced Hypersensitivity Syndrome
Author(s) -
Takeshi Saraya,
Michiaki Mikoshiba,
Harumi KAMIYAMA,
Masakazu Yoshizumi,
Shigeru Tsuchida,
Hiroyuki Tsukagoshi,
Taisei Ishioka,
Miho Terada,
Eiichi Tanabe,
Chizuko Tomioka,
Haruyuki Ishii,
Hirokazu Kimura,
Kunihisa Kozawa,
Tetsuo Shiohara,
Hajime Takizawa,
Hajime Goto
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00097-13
Subject(s) - pathological , lymphoma , medicine , human herpesvirus 6 , lymph node , pathology , generalized lymphadenopathy , drug , hypersensitivity reaction , immunology , herpesviridae , human immunodeficiency virus (hiv) , viral disease , pharmacology
The present case provides direct evidence of human herpesvirus 6 reactivation in resected lymph node tissue in a patient with drug-induced hypersensitivity syndrome. This case clearly demonstrates that appropriate pathological evaluation of lymphadenopathy for drug-induced hypersensitivity syndrome, which mimics malignant lymphoma in clinical, radiological, and pathological findings, is required.
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