Open AccessProteomics Analysis by Two-Dimensional Differential Gel Electrophoresis Reveals the Lack of a Broad Response of Neisseria meningitidis to In Vitro-Produced AI-2
Author(s) -
Stephan Schauder,
Lucia Penna,
Adeline Ritton,
Catherine Manin,
Fabienne Parker,
Geneviève Renauld-Mongénie
Publication year - 2005
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.187.1.392-395.2005
Subject(s) - neisseria meningitidis , biology , gel electrophoresis , mutant , proteomics , in vitro , strain (injury) , microbiology and biotechnology , proteome , neisseriaceae , biochemistry , bacteria , gene , genetics , antibiotics , anatomy
To investigate the effect of the autoinducer AI-2 on protein expression in Neisseria meningitidis, a luxS mutant of strain MC58 was grown in the presence and absence of in vitro-produced AI-2, and differential protein expression was assessed by two-dimensional differential gel electrophoresis. N. meningitidis did not show a global response to AI-2 signaling activity.