Open AccessThe Membrane Domain of SpoIIIE Is Required for Membrane Fusion during Bacillus subtilis Sporulation
Author(s) -
Marc D. Sharp,
Kit Pogliano
Publication year - 2003
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.185.6.2005-2008.2003
Subject(s) - bacillus subtilis , biology , membrane , fusion , cell membrane , microbiology and biotechnology , lipid bilayer fusion , biochemistry , genetics , bacteria , linguistics , philosophy
During Bacillus subtilis sporulation, SpoIIIE is required for both postseptational chromosome segregation and membrane fusion after engulfment. Here we demonstrate that SpoIIIE must be present in the mother cell to promote membrane fusion and that the N-terminal membrane-spanning segments constitute a minimal membrane fusion domain, as well as direct septal localization.