Open AccessThe Protein Encoded at the 3′ End of the Serine Protease Gene of Aeromonas sobria Functions as a Chaperone in the Production of the Protease
Author(s) -
Tomohiko Nomura,
Y. Fujii,
Hidetoshi Yamanaka,
Hidetomo Kobayashi,
Keinosuke Okamoto
Publication year - 2002
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.184.24.7058-7061.2002
Subject(s) - biology , operon , periplasmic space , serine protease , protease , chaperone (clinical) , open reading frame , tmprss6 , masp1 , biochemistry , serine , microbiology and biotechnology , gene , peptide sequence , enzyme , escherichia coli , pathology , medicine
For the successful production of Aeromonas sobria serine protease (ASP), open reading frame 2 (ORF2) protein, encoded at the 3' end of the protease operon, is required. In this study, we examined the action of ORF2 protein. The results showed that the protein associated with ASP in the periplasm and helped ASP to form an active structure.