Correction of the DNA Sequence of the regB Gene of Rhodobacter capsulatus with Implications for the Membrane Topology of the Sensor Kinase RegB | Zendy

Weizhen Chen | Zendy; Andreas Jäger | Zendy; Gabriele Klug | Zendy

Open Access

Correction of the DNA Sequence of the regB Gene of Rhodobacter capsulatus with Implications for the Membrane Topology of the Sensor Kinase RegB

Author(s) -

Weizhen Chen,

Andreas Jäger,

Gabriele Klug

Publication year - 2000

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.182.3.818-820.2000

Subject(s) - rhodobacter , biology , histidine kinase , transmembrane domain , transmembrane protein , gene , histidine , peptide sequence , membrane topology , computational biology , topology (electrical circuits) , biochemistry , amino acid , receptor , mutant , mathematics , combinatorics

We corrected the previously published sequence for theregB gene, which encodes a histidine sensor kinase inRhodobacter capsulatus . The deduced RegB amino acid sequence has an additional putative transmembrane domain at the N terminus. Analysis of RegB-PhoA and RegB-LacZ fusion proteins supports a topology model for RegB with six membrane-spanning domains.

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