Open AccessIntegration host factor amplifies the induction of the aceBAK operon of Escherichia coli by relieving IclR repression
Author(s) -
Ernesto Resnik,
Bin Pan,
Natarajan Ramani,
Martin Freundlich,
David C. LaPorte
Publication year - 1996
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.178.9.2715-2717.1996
Subject(s) - psychological repression , biology , lac operon , operon , escherichia coli , enzyme repression , microbiology and biotechnology , repressor , host (biology) , host factor , genetics , gene , gene expression
A binding site for integration host factor (IHF) was identified upstream of the aceBAK promoter. Under inducing conditions, IHF activates aceB::lacZ expression by opposing IclR repression. In contrast, IHF has little effect on aceB::lacZ expression under repressing conditions. The ability of IHF to relieve repression under inducing but not repressing conditions allows this protein to amplify the induction of aceBAK.