Open AccessThe insE open reading frame of IS1 is not required for formation of cointegrates
Author(s) -
Elaine Freund,
Miriam M. Susskind
Publication year - 1996
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.178.8.2420-2423.1996
Subject(s) - transposase , open reading frame , biology , transposition (logic) , transposable element , mutant , genetics , mutation , nonsense mutation , insertion sequence , peptide sequence , gene , computer science , missense mutation , artificial intelligence
The role of the insE open reading frame in transposition of IS1 was reexamined by using an insE nonsense mutation that does not alter the amino acid sequence of InsA inhibitor or InsAB transposase. The mutant was active in all strains tested, showing that insE is not essential for formation of cointegrates.