Open AccessTranscription of the Anabaena sp. strain PCC 7120 ntcA gene: multiple transcripts and NtcA binding
Author(s) -
T. Ramasubramanian,
Tingcun Wei,
Athenia Oldham,
James W. Golden
Publication year - 1996
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.178.3.922-926.1996
Subject(s) - biology , anabaena , transcription (linguistics) , gene , gene expression , promoter , transcription factor , binding site , dna binding protein , strain (injury) , limiting , genetics , regulation of gene expression , microbiology and biotechnology , cyanobacteria , bacteria , mechanical engineering , linguistics , philosophy , anatomy , engineering
The Anabaena sp. strain PCC 7120 ntcA gene showed multiple transcripts with different 5' ends. The relative abundance of transcripts varied in response to nitrogen availability. The ntcA product, NtcA, showed binding to the promoter region of its own gene. The binding site mapped to a region between the transcription start site used under nitrogen-replete conditions and the start sites used under nitrogen-limiting conditions, suggesting that NtcA regulates its own expression.