Open AccessIdentification of a Bacillus subtilis spo0H allele that is necessary for suppression of the sporulation-defective phenotype of a spo0A mutation
Author(s) -
M G Bramucci,
B D Green,
Nicholas P. Ambulos,
Philip Youngman
Publication year - 1995
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.177.6.1630-1633.1995
Subject(s) - biology , bacillus subtilis , mutation , mutant , genetics , sigma factor , allele , suppressor mutation , phenotype , gene , microbiology and biotechnology , gene product , rna polymerase , rna , gene expression , bacteria
A mutation in Bacillus subtilis spo0A codon 97 suppressed the sporulation defect caused by the spo0A9V mutation. The suppressor activity of the codon 97 mutation was evident only in the presence of a novel spo0H allele. Our results suggest that the spo0A gene product interacts with the sigma factor subunit of RNA polymerase.