Open AccessAnalysis of the genetic requirements for viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants
Author(s) -
Kenneth R. Peterson,
David W. Mount
Publication year - 1993
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.175.22.7505-7508.1993
Subject(s) - recbcd , biology , mutant , escherichia coli , genetics , dna repair , gene , dna , mutation , sos response , microbiology and biotechnology
RecBCD protein, necessary for Escherichia coli dam mutant viability, is directly required for DNA repair. Recombination genes recF+, recN+, recO+, and recQ+ are not essential for dam mutant viability; they are required for recBC sbcBC dam mutant survival. mutH, mutL, or mutS mutations do not suppress subinduction of SOS genes in dam mutants.