Open AccessGenes for 7S RNAs can replace the gene for 4.5S RNA in growth of Escherichia coli
Author(s) -
Stanley Brown
Publication year - 1991
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.173.5.1835-1837.1991
Subject(s) - biology , rna , escherichia coli , gene , small nucleolar rna , genetics , nucleic acid sequence , nucleotide , conserved sequence , non coding rna , sequence (biology) , microbiology and biotechnology , peptide sequence
4.5S RNAs of eubacteria and 7S RNAs of archaebacteria and eukaryotes exist in a hairpin conformation. The apex of this hairpin displays structural and sequence similarities among both 4.5S and 7S RNAs. Furthermore, a hyphenated sequence of 16 nucleotides is conserved in all eubacterial 4.5S RNAs examined. In this article I report that 7S RNAs that contain this 16-nucleotide sequence are able to replace 4.5S RNAs and permit growth of Escherichia coli.