Open AccessOsmotic regulation of PhoE porin synthesis in Escherichia coli
Author(s) -
Sabine Meyer,
Sandra Granett,
Jean-Luc Jung,
Merna Villarejo
Publication year - 1990
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.172.9.5501-5502.1990
Subject(s) - porin , biology , escherichia coli , osmotic concentration , betaine , bacterial outer membrane , biochemistry , osmotic shock , enterobacteriaceae , osmoregulation , regulon , microbiology and biotechnology , gene , ecology , salinity
In Escherichia coli, adaptation to hyperosmotic conditions alters the expression of the outer membrane porins OmpF and OmpC. The amount of PhoE porin, which is normally induced by phosphate deprivation, was greatly reduced in cells adapted to high-osmolarity conditions. Osmoregulation of PhoE operated independently of the activity of the PhoR phosphate sensor and did not involve cross-talk from the homologous osmosensor EnvZ. PhoE synthesis was partially restored by additional copies of the positive regulator phoB+ and by the osmoprotectant glycine betaine.