Open AccessInteraction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae
Author(s) -
J M Song,
Susan W. Liebman
Publication year - 1985
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.161.2.778-780.1985
Subject(s) - suppressor , biology , allele , saccharomyces cerevisiae , transfer rna , genetics , ribosome , yeast , gene , rna
Haploids bearing the dominant UAG suppressor, SUP7-a, and various alleles of the omnipotent suppressor sup35 were examined. The presence of the UAG suppressor reduced the efficiency of some alleles of sup35, and caused other sup35 alleles to be lethal. A nonclassical interaction of the dominant suppressor tRNA and the ribosome is proposed to explain these observations.
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