Molecular mechanisms of pyrimidine dimer excision in Saccharomyces cerevisiae: excision of dimers in cell extracts
Author(s) -
Richard Reynolds,
J. Love,
E C Friedberg
Publication year - 1981
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.147.2.705-708.1981
Subject(s) - pyrimidine dimer , saccharomyces cerevisiae , biology , thymine , nucleotide excision repair , dna , biochemistry , yeast , mutant , dimer , mutation , saccharomyces , microbiology and biotechnology , ultraviolet light , dna repair , gene , photochemistry , chemistry , organic chemistry
Cell-free extracts prepared from rad1-19, rd2-2, rad3-1, rad4-3, rad7-1, rad10-1, rd14-1, rad16-1, and cyc1-1 (rad7) mutants of Saccharomyces cerevisiae all catalyze the preferential excision of thymine-containing pyrimidine dimers from ultraviolet-irradiated DNA specifically incised with M. luteus ultraviolet deoxyribonucleic acid incising activity.
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