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Genome Sequence of Staphylococcus aureus VC40, a Vancomycin- and Daptomycin-Resistant Strain, To Study the Genetics of Development of Resistance to Currently Applied Last-Resort Antibiotics
Author(s) -
Peter Saß,
Anne Berscheid,
Andrea Jansen,
M. Oedenkoven,
Christiane Szekat,
Axel Strittmatter,
Gerhard Gottschalk,
Gabriele Bierbaum
Publication year - 2012
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.06631-11
Subject(s) - daptomycin , staphylococcus aureus , biology , antibiotics , whole genome sequencing , microbiology and biotechnology , genome , vancomycin , strain (injury) , antibiotic resistance , resistome , genetics , bacteria , gene , anatomy , integron
The increasing emergence of multidrug-resistant Staphylococcus aureus is a problem of global importance. Here, we report the genome of S. aureus VC40, which is resistant to the last-resort antibiotics vancomycin and daptomycin. Its genome sequence will allow insights into the mechanisms that convey full resistance to these compounds.

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