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Complete Genome Sequence of the Neonatal-Meningitis-Associated Escherichia coli Strain CE10
Author(s) -
Shuting Lu,
XiaoBing Zhang,
Yafang Zhu,
Kwang Sik Kim,
Jian Yang,
Qi Jin
Publication year - 2011
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.06284-11
Subject(s) - neonatal meningitis , biology , meningitis , escherichia coli , microbiology and biotechnology , whole genome sequencing , genome , strain (injury) , pathogen , pathogenesis , virology , gene , genetics , immunology , medicine , pediatrics , anatomy
Neonatal bacterial meningitis continues to be an important cause of mortality and morbidity worldwide. Escherichia coli possessing the K1 capsular polysaccharide is the most common Gram-negative pathogen causing neonatal meningitis. Here we present the complete genome sequence of neonatal meningitis-associated E. coli strain CE10, a unique K1 strain with a functional type III secretion system. Functional analysis of the genome should enhance our knowledge of the pathogenesis of neonatal E. coli K1 meningitis.

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