Complete Genome Sequences of Three Pseudomonas aeruginosa Isolates with Phenotypes of Polymyxin B Adaptation and Inducible Resistance | Zendy

Brian Boyle | Zendy; Lucía Fernández | Zendy; Jérôme Laroche | Zendy; Iréna Kukavica-Ibrulj | Zendy; Carlos Maurício Cardeal Mendes | Zendy; Robert Hancock | Zendy; Roger C. Lévesque | Zendy

Open Access

Complete Genome Sequences of Three Pseudomonas aeruginosa Isolates with Phenotypes of Polymyxin B Adaptation and Inducible Resistance

Author(s) -

Brian Boyle,

Lucía Fernández,

Jérôme Laroche,

Iréna Kukavica-Ibrulj,

Carlos Maurício Cardeal Mendes,

Robert Hancock,

Roger C. Lévesque

Publication year - 2011

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.06246-11

Subject(s) - biology , pseudomonas aeruginosa , polymyxin , polymyxin b , phenotype , microbiology and biotechnology , adaptation (eye) , genetics , genome , pseudomonadales , pseudomonadaceae , whole genome sequencing , bacteria , gene , neuroscience

Clinical "superbug" isolates of Pseudomonas aeruginosa were previously observed to be resistant to several antibiotics, including polymyxin B, and/or to have a distinct, reproducible adaptive polymyxin resistance phenotype, identified by observing "skipped" wells (appearance of extra turbid wells) during broth microdilution testing. Here we report the complete assembled draft genome sequences of three such polymyxin resistant P. aeruginosa strains (9BR, 19BR, and 213BR).

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