Decay of a Model mRNA in Bacillus subtilis by a Combination of RNase J1 5′ Exonuclease and RNase Y Endonuclease Activities | Zendy

Shiyi Yao | Zendy; Jamie Richards | Zendy; Joel G. Belasco | Zendy; David H. Bechhofer | Zendy

Open Access

Decay of a Model mRNA in Bacillus subtilis by a Combination of RNase J1 5′ Exonuclease and RNase Y Endonuclease Activities

Author(s) -

Shiyi Yao,

Jamie Richards,

Joel G. Belasco,

David H. Bechhofer

Publication year - 2011

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.05939-11

Subject(s) - exonuclease , biology , rnase p , endonuclease , bacillus subtilis , messenger rna , rnase mrp , rnase h , microbiology and biotechnology , rnase ph , enzyme , genetics , biochemistry , rna , gene , bacteria , dna polymerase

The involvement of the recently characterized 5′ exonuclease activity of RNase J1 and endonuclease activity of RNase Y in the turnover of ΔermC mRNA inBacillus subtilis was investigated. Evidence is presented that both of these activities determine the half-life of ΔermC mRNA.

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