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The involvement of the recently characterized 5′ exonuclease activity of RNase J1 and endonuclease activity of RNase Y in the turnover of ΔermC mRNA inBacillus subtilis was investigated. Evidence is presented that both of these activities determine the half-life of ΔermC mRNA.

Decay of a Model mRNA in Bacillus subtilis by a Combination of RNase J1 5′ Exonuclease and RNase Y Endonuclease Activities