Campylobacter jejuniCsrA Mediates Oxidative Stress Responses, Biofilm Formation, and Host Cell Invasion | Zendy

Joshua A. Fields | Zendy; Stuart A. Thompson | Zendy

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Campylobacter jejuniCsrA Mediates Oxidative Stress Responses, Biofilm Formation, and Host Cell Invasion

Author(s) -

Joshua A. Fields,

Stuart A. Thompson

Publication year - 2008

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01928-07

Subject(s) - campylobacter jejuni , biology , microbiology and biotechnology , biofilm , oxidative stress , mutant , regulator , campylobacter , pathogenesis , bacteria , genetics , immunology , gene , biochemistry

The putative global posttranscriptional regulator csrA was mutated in Campylobacter jejuni 81-176. The csrA mutant was attenuated in surviving oxidative stress. CsrA also contributed to biofilm formation and adherence to and invasion of INT407 intestinal epithelial cells, suggesting a regulatory role for CsrA in C. jejuni pathogenesis.

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