Rrp2, a σ 54 -Dependent Transcriptional Activator of Borrelia burgdorferi , Activates rpoS in an Enhancer-Independent Manner | Zendy

Jon S. Blevins | Zendy; HaiJun Xu | Zendy; Ming He | Zendy; Michael V. Norgard | Zendy; Larry Reitzer | Zendy; Xiaoming Yang | Zendy

Open Access

Rrp2, a σ ⁵⁴ -Dependent Transcriptional Activator of Borrelia burgdorferi , Activates rpoS in an Enhancer-Independent Manner

Author(s) -

Jon S. Blevins,

HaiJun Xu,

Ming He,

Michael V. Norgard,

Larry Reitzer,

Xiaoming Yang

Publication year - 2009

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01721-08

Subject(s) - rpos , biology , enhancer , borrelia burgdorferi , activator (genetics) , recombinant dna , transcription (linguistics) , microbiology and biotechnology , dna , borrelia , promoter , genetics , gene , gene expression , philosophy , antibody , linguistics

Rrp2 is the sole σ54 -dependent transcriptional activator present in theBorrelia burgdorferi genome. We showed that recombinant Rrp2 binds to DNA in a sequence-nonspecific manner. During infection, Rrp2 activates σ54 -dependentrpoS expression without an apparent upstream enhancer element commonly associated with other σ54 -dependent transcriptional activators.

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