Whole-Genome Sequence of Livestock-Associated ST398 Methicillin-Resistant Staphylococcus aureus Isolated from Humans in Canada | Zendy

George R. Golding | Zendy; Louis Bryden | Zendy; Paul N. Levett | Zendy; Ryan R. McDonald | Zendy; Alice Wong | Zendy; Morag Graham | Zendy; Shaun Tyler | Zendy; Gary Van Domselaar | Zendy; Philip Mabon | Zendy; Heather Kent | Zendy; Patrick Butaye | Zendy; Tara C. Smith | Zendy; Kristina Kadlec | Zendy; Štefan Schwarz | Zendy; S.J. Weese | Zendy; Michael R. Mulvey | Zendy

Open Access

Whole-Genome Sequence of Livestock-Associated ST398 Methicillin-Resistant Staphylococcus aureus Isolated from Humans in Canada

Author(s) -

George R. Golding,

Louis Bryden,

Paul N. Levett,

Ryan R. McDonald,

Alice Wong,

Morag Graham,

Shaun Tyler,

Gary Van Domselaar,

Philip Mabon,

Heather Kent,

Patrick Butaye,

Tara C. Smith,

Kristina Kadlec,

Štefan Schwarz,

S.J. Weese,

Michael R. Mulvey

Publication year - 2012

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01680-12

Subject(s) - biology , staphylococcus aureus , methicillin resistant staphylococcus aureus , whole genome sequencing , livestock , genome , colonization , staphylococcal infections , population , incidence (geometry) , microbiology and biotechnology , veterinary medicine , genetics , gene , bacteria , environmental health , ecology , medicine , physics , optics

Despite reports of high colonization rates of ST398 livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) among pigs and pig farmers, the incidence of LA-MRSA infection in the general population in Canada appears to be rare in comparison to that in some European countries. In this study, the complete genome sequence of a Canadian representative LA-MRSA isolate (08BA02176) from a human postoperative surgical site infection was acquired and compared to the sequenced genome of an LA-MRSA isolate (S0385) from Europe to identify genetic traits that may explain differences in the success of these particular strains in some locales.

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