Wall Teichoic Acid-Dependent Adsorption of Staphylococcal Siphovirus and Myovirus | Zendy

Guoqing Xia | Zendy; Rebecca M. Corrigan | Zendy; Volker Winstel | Zendy; Christiane Goerke | Zendy; Angelika Gründling | Zendy; Andreas Peschel | Zendy

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Wall Teichoic Acid-Dependent Adsorption of Staphylococcal Siphovirus and Myovirus

Author(s) -

Guoqing Xia,

Rebecca M. Corrigan,

Volker Winstel,

Christiane Goerke,

Angelika Gründling,

Andreas Peschel

Publication year - 2011

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01412-10

Subject(s) - teichoic acid , lipoteichoic acid , biology , cell wall , microbiology and biotechnology , staphylococcus aureus , mutant , staphylococcus , peptidoglycan , biochemistry , bacteria , genetics , gene

The molecular interactions between staphylococcal phages and host cell surfaces are poorly understood. Employing Staphylococcus aureus teichoic acid mutants, we demonstrate that wall teichoic acid (WTA), but not lipoteichoic acid, serves as a receptor for staphylococcal siphovirus and myovirus, while only the siphovirus requires glycosylated WTA.

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