Bacteroides fragilis Synthesizes a DNA Invertase Affecting both a Local and a Distant Region | Zendy

Hazeline Roche-Håkansson | Zendy; Maria ChatzidakiLivanis | Zendy; Michael J. Coyne | Zendy; Laurie E. Comstock | Zendy

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Bacteroides fragilis Synthesizes a DNA Invertase Affecting both a Local and a Distant Region

Author(s) -

Hazeline Roche-Håkansson,

Maria ChatzidakiLivanis,

Michael J. Coyne,

Laurie E. Comstock

Publication year - 2006

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01362-06

Subject(s) - biology , bacteroides fragilis , dna , invertase , microbiology and biotechnology , computational biology , genetics , bacteria , biochemistry , enzyme

The activity of a fourth conserved tyrosine site-specific recombinase (Tsr) of Bacteroides fragilis was characterized. Its gene, tsr19, is adjacent to mpi, encoding the global DNA invertase regulating capsular polysaccharide biosynthesis. Unlike the other described Tsrs of B. fragilis, Tsr19 brings about inversion of two DNA regions, one local and one located distantly.

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