Requirement of the agr Locus for Colony Spreading of Staphylococcus aureus | Zendy

Eleni Tsompanidou | Zendy; Mark J. J. B. Sibbald | Zendy; Monika A. Chlebowicz | Zendy; Annette Dreisbach | Zendy; Jaap Willem Back | Zendy; Jan Maarten van Dijl | Zendy; Girbe Buist | Zendy; Emma L. Denham | Zendy

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Requirement of the agr Locus for Colony Spreading of Staphylococcus aureus

Author(s) -

Eleni Tsompanidou,

Mark J. J. B. Sibbald,

Monika A. Chlebowicz,

Annette Dreisbach,

Jaap Willem Back,

Jan Maarten van Dijl,

Girbe Buist,

Emma L. Denham

Publication year - 2010

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01276-10

Subject(s) - biology , staphylococcus aureus , virulence , microbiology and biotechnology , quorum sensing , locus (genetics) , pathogen , human pathogen , agar plate , genetics , gene , bacteria

The important human pathogen Staphylococcus aureus is known to spread on soft agar plates. Here, we show that colony spreading of S. aureus involves the agr quorum-sensing system. This finding can be related to the agr-dependent expression of biosurfactants, such as phenol-soluble modulins, suggesting a connection between spreading motility and virulence.

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