YhbO Protects Cells against Multiple Stresses | Zendy

Jad Abdallah | Zendy; Teresa Caldas | Zendy; Fatoum Kthiri | Zendy; Renée Kern | Zendy; Gilbert Richarme | Zendy

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YhbO Protects Cells against Multiple Stresses

Author(s) -

Jad Abdallah,

Teresa Caldas,

Fatoum Kthiri,

Renée Kern,

Gilbert Richarme

Publication year - 2007

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01208-07

Subject(s) - biology , escherichia coli , mutant , cysteine , oxidative stress , microbiology and biotechnology , biochemistry , genetics , gene , enzyme

YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management.

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