Translational Defects in a Mutant Deficient in YajL, the Bacterial Homolog of the Parkinsonism-Associated Protein DJ-1 | Zendy

Fatoum Kthiri | Zendy; Valérie Gautier | Zendy; Hai-Tuong Le | Zendy; Marie-Françoise Prère | Zendy; Olivier Fayet | Zendy; Abderrahim Malki | Zendy; Ahmed Landoulsi | Zendy; Gilbert Richarme | Zendy

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Translational Defects in a Mutant Deficient in YajL, the Bacterial Homolog of the Parkinsonism-Associated Protein DJ-1

Author(s) -

Fatoum Kthiri,

Valérie Gautier,

Hai-Tuong Le,

Marie-Françoise Prère,

Olivier Fayet,

Abderrahim Malki,

Ahmed Landoulsi,

Gilbert Richarme

Publication year - 2010

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.01077-10

Subject(s) - ribosome , biology , ribosomal protein , mutant , escherichia coli , translation (biology) , protein biosynthesis , 30s , ribosomal rna , 50s , biochemistry , genetics , rna , gene , messenger rna

We report here that YajL is associated with ribosomes and interacts with many ribosomal proteins and that a yajL mutant of Escherichia coli displays decreased translation accuracy, as well as increased dissociation of 70S ribosomes into 50S and 30S subunits after oxidative stress.

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