Open AccessMultiple Two-Component Systems of Streptococcus mutans Regulate Agmatine Deiminase Gene Expression and Stress Tolerance
Author(s) -
Yaling Liu,
Robert A. Burne
Publication year - 2009
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.01054-09
Subject(s) - streptococcus mutans , agmatine , biology , arginine deiminase , two component regulatory system , microbiology and biotechnology , gene expression , gene , genetics , enzyme , biochemistry , bacteria , arginine , amino acid , mutant , putrescine
Induction of the agmatine deiminase system (AgDS) ofStreptococcus mutans requires agmatine and is optimal at low pH. We show here that the VicRK, ComDE, and CiaRH two-component systems influence AgDS gene expression in response to acidic and thermal stresses.