Draft Genome Sequence of Streptomyces clavuligerus NRRL 3585, a Producer of Diverse Secondary Metabolites | Zendy

Ju Yeon Song | Zendy; Haeyoung Jeong | Zendy; Dong Yu | Zendy; Michael A. Fischbach | Zendy; Hong-Seog Park | Zendy; Jae Jong Kim | Zendy; JeongSun Seo | Zendy; Susan E. Jensen | Zendy; Tae Kwang Oh | Zendy; Kye Joon Lee | Zendy; Jihyun F. Kim | Zendy

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Draft Genome Sequence of Streptomyces clavuligerus NRRL 3585, a Producer of Diverse Secondary Metabolites

Author(s) -

Ju Yeon Song,

Haeyoung Jeong,

Dong Yu,

Michael A. Fischbach,

Hong-Seog Park,

Jae Jong Kim,

JeongSun Seo,

Susan E. Jensen,

Tae Kwang Oh,

Kye Joon Lee,

Jihyun F. Kim

Publication year - 2010

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00859-10

Subject(s) - streptomyces clavuligerus , biology , whole genome sequencing , genome , genetics , pyrosequencing , streptomyces , clavulanic acid , gene , plasmid , computational biology , antibiotics , actinomycetales , bacteria , amoxicillin

Streptomyces clavuligerus is an important industrial strain that produces a number of antibiotics, including clavulanic acid and cephamycin C. A high-quality draft genome sequence of the S. clavuligerus NRRL 3585 strain was produced by employing a hybrid approach that involved Sanger sequencing, Roche/454 pyrosequencing, optical mapping, and partial finishing. Its genome, comprising four linear replicons, one chromosome, and four plasmids, carries numerous sets of genes involved in the biosynthesis of secondary metabolites, including a variety of antibiotics.

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