Open AccessAssemblies of DivIVA Mark Sites for Hyphal Branching and Can Establish New Zones of Cell Wall Growth in Streptomyces coelicolor
Author(s) -
Antje M. Hempel,
Sheng Bing Wang,
Michal Letek,
José A. Gil,
Klas Flärdh
Publication year - 2008
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00839-08
Subject(s) - streptomyces coelicolor , biology , streptomyces , hypha , microbiology and biotechnology , peptidoglycan , cell wall , cell cycle protein , cell , botany , cell cycle , genetics , bacteria
Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces.