Fitness Effects of Replichore Imbalance in Salmonella enterica | Zendy

T. David Matthews | Zendy; Stanley Maloy | Zendy

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Fitness Effects of Replichore Imbalance in Salmonella enterica

Author(s) -

T. David Matthews,

Stanley Maloy

Publication year - 2010

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00649-10

Subject(s) - salmonella enterica , biology , salmonella , genetics , transposable element , chromosome , genetic fitness , serotype , gene , mutant , microbiology and biotechnology , bacteria

A fitness cost due to imbalanced replichores has been proposed to provoke chromosome rearrangements in Salmonella enterica serovars. To determine the impact of replichore imbalance on fitness, the relative fitness of isogenic Salmonella strains containing transposon-held duplications of various sizes and at various chromosomal locations was determined. Although duplication of certain genes influenced fitness, a replichore imbalance of up to 16° did not affect fitness.

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