Open AccessGenomic Analysis of the Role of RNase R in the Turnover of Pseudomonas putida mRNAs
Author(s) -
Pilar Fonseca,
Renata Moreno,
Fernando Rojo
Publication year - 2008
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00630-08
Subject(s) - biology , pseudomonas putida , exoribonuclease , rnase p , rnase mrp , transcriptome , genetics , gene , rnase ph , gene expression , rna
RNase R is a 3'-5' highly processive exoribonuclease that can digest RNAs with extensive secondary structure. We analyzed the global effect of eliminating RNase R on the Pseudomonas putida transcriptome and the expression of the rnr gene under diverse conditions. The absence of RNase R led to increased levels of many mRNAs, indicating that it plays an important role in mRNA turnover.
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