Genome Sequence of the Milbemycin-Producing Bacterium Streptomyces bingchenggensis
Author(s) -
Xiang-Jing Wang,
Yi-Jun Yan,
Bo Zhang,
Jing An,
Ji-Jia Wang,
Jun Tian,
Ling Jiang,
Yihua Chen,
ShengXiong Huang,
Min Yin,
Ji Zhang,
Ai-Li Gao,
Chong-Xi Liu,
ZhaoXiang Zhu,
Wen-Sheng Xiang
Publication year - 2010
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00596-10
Subject(s) - biology , whole genome sequencing , streptomyces , genome , strain (injury) , bacteria , antibiotics , genetics , microbiology and biotechnology , streptomycetaceae , sequence (biology) , actinomycetales , gene , anatomy
Streptomyces bingchenggensis is a soil-dwelling bacterium producing the commercially important anthelmintic macrolide milbemycins. Besides milbemycins, the insecticidal polyether antibiotic nanchangmycin and some other antibiotics have also been isolated from this strain. Here we report the complete genome sequence of S. bingchenggensis. The availability of the genome sequence of S. bingchenggensis should enable us to understand the biosynthesis of these structurally intricate antibiotics better and facilitate rational improvement of this strain to increase their titers.
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