Open AccessIsoprenoids Are Essential for Fruiting Body Formation in Myxococcus xanthus
Author(s) -
Wolfram Lorenzen,
Michael W. Ring,
Gertrud Schwär,
Helge B. Bode
Publication year - 2009
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00539-09
Subject(s) - myxococcus xanthus , biology , mutant , myxobacteria , biochemistry , biosynthesis , bacteria , gene , genetics
It was recently shown that Myxococcus xanthus harbors an alternative and reversible biosynthetic pathway to isovaleryl coenzyme A (CoA) branching from 3-hydroxy-3-methylglutaryl-CoA. Analyses of various mutants in these pathways for fatty acid profiles and fruiting body formation revealed for the first time the importance of isoprenoids for myxobacterial development.
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