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The staphylococcal accessory regulator SarA and the alternative sigma factor sigma(B) have been previously identified as positive regulators, and IcaR as a negative regulator, of icaADBC expression. Here, we show that in Staphylococcus aureus SarA and sigma(B) are also required for icaR expression and that IcaR does not have a significant effect on its own expression.

Regulation of the Intercellular Adhesin Locus Regulator ( icaR ) by SarA, σ B , and IcaR in Staphylococcus aureus

Regulation of the Intercellular Adhesin Locus Regulator ( icaR ) by SarA, σ ^B , and IcaR in Staphylococcus aureus