Regulation of the Intercellular Adhesin Locus Regulator ( icaR ) by SarA, σ B , and IcaR in Staphylococcus aureus | Zendy

Nuno Cerca | Zendy; Jamie L. Brooks | Zendy; Kimberly K. Jefferson | Zendy

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Regulation of the Intercellular Adhesin Locus Regulator ( icaR ) by SarA, σ ^B , and IcaR in Staphylococcus aureus

Author(s) -

Nuno Cerca,

Jamie L. Brooks,

Kimberly K. Jefferson

Publication year - 2008

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00482-08

Subject(s) - biology , staphylococcus aureus , bacterial adhesin , intracellular , microbiology and biotechnology , locus (genetics) , regulator , genetics , bacteria , escherichia coli , gene

The staphylococcal accessory regulator SarA and the alternative sigma factor sigma(B) have been previously identified as positive regulators, and IcaR as a negative regulator, of icaADBC expression. Here, we show that in Staphylococcus aureus SarA and sigma(B) are also required for icaR expression and that IcaR does not have a significant effect on its own expression.

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