Open AccessWhole-Genome Sequences of Four Mycobacterium bovis BCG Vaccine Strains
Author(s) -
Yuanlong Pan,
Xi Yang,
Jia Duan,
Na Lü,
Andrea S. Leung,
Vanessa Tran,
Yongfei Hu,
Na Wu,
Di Liu,
Zhiming Wang,
Xiaohong Yu,
Chen Chen,
Yuanyuan Zhang,
Kanglin Wan,
Jun Liu,
Baoli Zhu
Publication year - 2011
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00405-11
Subject(s) - mycobacterium bovis , biology , bcg vaccine , mycobacterium tuberculosis , whole genome sequencing , microbiology and biotechnology , genome , tuberculosis , virology , mycobacterium , mycobacterium tuberculosis complex , genetics , vaccination , bacteria , gene , medicine , pathology
Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only vaccine available against tuberculosis (TB). A number of BCG strains are in use, and they exhibit biochemical and genetic differences. We report the genome sequences of four BCG strains representing different lineages, which will help to design more effective TB vaccines.