The Mycobacterium-Specific Gene Rv2719c Is DNA Damage Inducible Independently of RecA | Zendy

Patricia C. Brooks | Zendy; Lisa F. Dawson | Zendy; Lucinda Rand | Zendy; Elaine O. Davis | Zendy

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The Mycobacterium-Specific Gene Rv2719c Is DNA Damage Inducible Independently of RecA

Author(s) -

Patricia C. Brooks,

Lisa F. Dawson,

Lucinda Rand,

Elaine O. Davis

Publication year - 2006

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00340-06

Subject(s) - biology , dna , gene , genetics , dna damage , bacterial protein , mycobacterium , microbiology and biotechnology , bacteria

The mycobacterium-specific gene Rv2719c was found to be expressed primarily from a promoter that was clearly DNA damage inducible independently of RecA. Upstream of the transcriptional start site for this promoter, sequence motifs resembling those observed previously at the RecA-independent, DNA damage-induciblerecA promoter were identified, and the −10 motif was demonstrated by mutational analysis in transcriptional fusion constructs to be important for expression of Rv2719c.

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