Noncanonical Translation Initiation Comes of Age | Zendy

Paul Babitzke | Zendy; Michael B. O’Connor | Zendy

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Noncanonical Translation Initiation Comes of Age

Author(s) -

Paul Babitzke,

Michael B. O’Connor

Publication year - 2017

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00295-17

Subject(s) - biology , translation (biology) , mechanism (biology) , genetics , eukaryotic translation , computational biology , evolutionary biology , pairing , messenger rna , gene , physics , superconductivity , quantum mechanics

The canonical translation initiation mechanism involves base pairing between the mRNA and 16S rRNA. However, a variety of identified mechanisms deviate from this conventional route. Beck and Janssen (J Bacteriol 199:e00091-17, 2017, https://doi.org/10.1128/JB.00091-17) have recently described another noncanonical mode of translation initiation. Here, we describe how this process differs from previously reported mechanisms, with the hope that it will foster increased awareness of the diversity of regulatory mechanisms that await discovery.

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