Frequency and Rate of Pilin Antigenic Variation of Neisseria meningitidis
Author(s) -
R. Allen Helm,
H. Steven Seifert
Publication year - 2010
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00280-10
Subject(s) - pilin , neisseria gonorrhoeae , pilus , biology , neisseria meningitidis , antigenic variation , strain (injury) , microbiology and biotechnology , neisseriaceae , antigen , neisseria , virology , genetics , bacteria , virulence , gene , anatomy , antibiotics
The rates of pilin antigenic variation (Av) of two strains of Neisseria meningitidis were determined using an unbiased DNA sequencing assay. Strain MC58 underwent pilin Av at a rate similar to that of N. gonorrhoeae strain MS11 but lower than that of N. gonorrhoeae strain FA1090. Pilin Av was undetectable in strain FAM18.
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