Pseudomonas aeruginosa tssC1 Links Type VI Secretion and Biofilm-Specific Antibiotic Resistance | Zendy

Li Zhang | Zendy; Aaron Hinz | Zendy; Jean-Paul Nadeau | Zendy; ThienFah Mah | Zendy

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Pseudomonas aeruginosa tssC1 Links Type VI Secretion and Biofilm-Specific Antibiotic Resistance

Author(s) -

Li Zhang,

Aaron Hinz,

Jean-Paul Nadeau,

ThienFah Mah

Publication year - 2011

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00268-11

Subject(s) - biofilm , pseudomonas aeruginosa , microbiology and biotechnology , biology , antibiotics , secretion , antibiotic resistance , type three secretion system , bacteria , gene , virulence , genetics , biochemistry

Biofilm-specific antibiotic resistance is influenced by multiple factors. We demonstrated thatPseudomonas aeruginosa tssC1 , a gene implicated in type VI secretion (T6S), is important for resistance of biofilms to a subset of antibiotics. We showed thattssC1 expression is induced in biofilms and confirmed thattssC1 is required for T6S.

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