CRISPR Genome Editing Systems in the Genus Clostridium : a Timely Advancement | Zendy

Kathleen N. McAllister | Zendy; Joseph A. Sorg | Zendy

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CRISPR Genome Editing Systems in the Genus Clostridium : a Timely Advancement

Author(s) -

Kathleen N. McAllister,

Joseph A. Sorg

Publication year - 2019

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00219-19

Subject(s) - crispr , biology , clostridia , repurposing , cas9 , genome editing , computational biology , clostridium , crispr interference , metagenomics , genetics , bacteria , gene , ecology

The genusClostridium is composed of bioproducers, which are important for the industrial production of chemicals, as well as pathogens, which are a significant burden to the patients and on the health care industry. Historically, even though these bacteria are well known and are commonly studied, the genetic technologies to advance our understanding of these microbes have lagged behind other systems. New tools would continue the advancement of our understanding of clostridial physiology.

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