Spontaneous Amplification of the Actinorhodin Gene Cluster in Streptomyces coelicolor Involving Native Insertion Sequence IS 466 | Zendy

Elizabeth M. Widenbrant | Zendy; HsiuHui Tsai | Zendy; Carton W. Chen | Zendy; Camilla M. Kao | Zendy

Open Access

Spontaneous Amplification of the Actinorhodin Gene Cluster in Streptomyces coelicolor Involving Native Insertion Sequence IS 466

Author(s) -

Elizabeth M. Widenbrant,

HsiuHui Tsai,

Carton W. Chen,

Camilla M. Kao

Publication year - 2008

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00131-08

Subject(s) - actinorhodin , streptomyces coelicolor , biology , genetics , transposable element , gene , streptomyces , gene cluster , chromosome , insertion sequence , streptomycetaceae , actinomycetales , bacteria , genome

We observed a spontaneous amplification of the Streptomyces coelicolor chromosome, including genes encoding biosynthetic enzymes of the antibiotic actinorhodin. A new junction of two tandem segments has, inserted within it, a third copy of a transposable element existing in two places elsewhere in the chromosome, suggesting its involvement in the amplification mechanism.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research