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The Legacy of HfrH: Mutations in the Two-Component System CreBC Are Responsible for the Unusual Phenotype of an Escherichia coli arcA Mutant
Author(s) -
Pablo I. Nikel,
Alejandra de Almeida,
M. Julia Pettinari,
Beatriz S. Méndez
Publication year - 2008
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00040-08
Subject(s) - biology , mutant , phenotype , mutation , escherichia coli , genetics , gene , transduction (biophysics) , lineage (genetic) , biochemistry
Strains derived from HfrH carrying the arcA2 null mutation exhibit a higher respiratory rate, enhanced glucose consumption, and a more-reduced intracellular redox state than arcA deletion mutants of a different lineage. The phenotype of the arcA2 mutants was due to the presence of a creC constitutive mutation introduced by P1 transduction.

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